Also available in ResearchGate and Google scholar
Wu, H. H., Symersky, J., and Lu, M. (2020) Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily, Sci Rep 10, 3949.
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Wu, H. H., Symersky, J., and Lu, M. (2019) Structure of an engineered multidrug transporter MdfA reveals the molecular basis for substrate recognition, Commun Biol 2, 210. (recommended by Faculty 1000)
Hsin-Hui Wu et al. present the structure of the I239T/G354E variant of the MdfA multidrug transporter in complex with three different ligands. They find that this variant has two discrete, non-overlapping substrate binding sites, leading to differential interactions with ligands compared to wild-type MdfA.
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Lin, J. S., Pissaridou, P., Wu, H. H., Tsai, M. D., Filloux, A., and Lai, E. M.* (2018) TagF-mediated repression of bacterial type VI secretion systems involves a direct interaction with the cytoplasmic protein Fha, J Biol Chem293, 8829-8842.
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Chen, K. H.*, Chuankhayan, P., Wu, H. H., Chen, C. J.*, Fukuda, M., Yu, S. S., and Chan, S. I. (2015) The bacteriohemerythrin from Methylococcus capsulatus (Bath): Crystal structures reveal that Leu114 regulates a water tunnel, J Inorg Biochem 150, 81-89. (Dr. Kelvin H.-C. Chen is the advisor of my master thesis) PDF
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Lin, J. S., Wu, H. H., Hsu, P. H., Ma, L. S., Pang, Y. Y., Tsai, M. D., and Lai, E. M.* (2014) Fha interaction with phosphothreonine of TssL activates type VI secretion in Agrobacterium tumefaciens, PLoS Pathog 10, e1003991. (Highlighted in the front page of Academia Sinica website) PDF
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Chen, K. H.*, Wu, H. H., Ke, S. F., Rao, Y. T., Tu, C. M., Chen, Y. P., Kuei, K. H., Chen, Y. S., Wang, V. C., Kao, W. C., and Chan, S. I (2012) Bacteriohemerythrin bolsters theactivity of the particulate methane monooxygenase (pMMO) in Methylococcus capsulatus (Bath), J Inorg Biochem 111, 10-17. (Dr. Kelvin H.-C. Chen is the advisor of my master thesis) PDF
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Wu, H. H., Wu, P. Y., Huang, K. F., Kao, Y. Y., and Tsai, M. D.* (2012) Structural delineation of MDC1-FHAdomain binding with CHK2-pThr68, Biochemistry 51, 575-577. (Highlighted in the front page of Biochemistry website) PDF
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